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But when combined with GLP-1 activity, the glucose-raising effect is neutralized while the energy expenditure benefits remain

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Recommendation Use for 46 weeks Then take a 24 week break This break allows NNMT levels to rebound and resensitizes the body to the peptides metabolic signaling

Subsequent interest in AOD-9604 has been limited to niche research areas, particularly osteoarthritis, where intra-articular injection might bypass systemic bioavailability limitations